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Identification of Multiple Novel Protein Biomarkers Shed by Human Serous Ovarian Tumors into the Blood of Immunocompromised Mice and Verified in Patient Sera
The most cancer-specific biomarkers in blood are likely to be proteins shed directly by the tumor rather than less specific inflammatory or other host responses. The use of xenograft mouse models together with in-depth proteome analysis for identification of human proteins in the mouse blood is an u...
Autores principales: | Beer, Lynn A., Wang, Huan, Tang, Hsin-Yao, Cao, Zhijun, Chang-Wong, Tony, Tanyi, Janos L., Zhang, Rugang, Liu, Qin, Speicher, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609810/ https://www.ncbi.nlm.nih.gov/pubmed/23544127 http://dx.doi.org/10.1371/journal.pone.0060129 |
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