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Sex Determining Region Y-Box 2 (SOX2) Amplification Is an Independent Indicator of Disease Recurrence in Sinonasal Cancer

OBJECTIVES: The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells. Recently, amplification of the SOX2 gene locus has been described in squamous cell carcinoma (SCC) of different organ site...

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Detalles Bibliográficos
Autores principales: Schröck, Andreas, Göke, Friederike, Wagner, Patrick, Bode, Maike, Franzen, Alina, Braun, Martin, Huss, Sebastian, Agaimy, Abbas, Ihrler, Stephan, Menon, Ropika, Kirsten, Robert, Kristiansen, Glen, Bootz, Friedrich, Lengerke, Claudia, Perner, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609820/
https://www.ncbi.nlm.nih.gov/pubmed/23544055
http://dx.doi.org/10.1371/journal.pone.0059201