Nuclear localization signals in phage terminal proteins provide a novel gene delivery tool in mammalian cells

Terminal proteins (TPs) of bacteriophages prime DNA replication and become covalently linked to the genome ends. Unexpectedly, we have found functional eukaryotic nuclear localization signals (NLSs) within the TP sequences of bacteriophages from diverse families and hosts. Given the role of bacterio...

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Detalles Bibliográficos
Autores principales: Redrejo-Rodríguez, Modesto, Muñoz-Espín, Daniel, Holguera, Isabel, Mencía, Mario, Salas, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Article Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609834/
https://www.ncbi.nlm.nih.gov/pubmed/23750294
http://dx.doi.org/10.4161/cib.22829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609834/
https://www.ncbi.nlm.nih.gov/pubmed/23750294
http://dx.doi.org/10.4161/cib.22829

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