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Inter-organellar communication with mitochondria regulates both the intrinsic and extrinsic pathways of apoptosis

One of our major research interests is to define BCL-2 family function in the cellular decision to induce mitochondrial outer membrane permeabilization and apoptosis. Curiosity in BCL-2 family - mitochondrial interactions led to the identification that the sphingolipid pathway plays a crucial role i...

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Detalles Bibliográficos
Autores principales: Renault, Thibaud T., Chipuk, Jerry E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609836/
https://www.ncbi.nlm.nih.gov/pubmed/23750296
http://dx.doi.org/10.4161/cib.22872