Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression

The causes of major depression remain unknown. Antidepressants elevate monoamine concentrations, particularly serotonin, but it remains uncertain which downstream events are critical to their therapeutic effects. We report that endogenous serotonin selectively potentiated excitatory synapses formed...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Xiang, Kallarackal, Angy J., Kvarta, Mark D., Goluskin, Sasha, Gaylor, Kaitlin, Bailey, Aileen M., Lee, Hey-Kyoung, Huganir, Richard L., Thompson, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609911/
https://www.ncbi.nlm.nih.gov/pubmed/23502536
http://dx.doi.org/10.1038/nn.3355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609911/
https://www.ncbi.nlm.nih.gov/pubmed/23502536
http://dx.doi.org/10.1038/nn.3355

Ejemplares similares