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Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression
The causes of major depression remain unknown. Antidepressants elevate monoamine concentrations, particularly serotonin, but it remains uncertain which downstream events are critical to their therapeutic effects. We report that endogenous serotonin selectively potentiated excitatory synapses formed...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609911/ https://www.ncbi.nlm.nih.gov/pubmed/23502536 http://dx.doi.org/10.1038/nn.3355 |