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Expression of HSV-1 Receptors in EBV-Associated Lymphoproliferative Disease Determines Susceptibility to Oncolytic HSV

Epstein-Barr virus (EBV)-associated B cell lymphoproliferative disease (LPD) after hematopoietic stem cell or solid organ transplantation remains a life-threatening complication. Expression of the virus-encoded gene product, EBER, has been shown to prevent apoptosis via blockade of PKR activation. B...

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Detalles Bibliográficos
Autores principales: Wang, Pin-Yi, Currier, Mark A, Hansford, Loen, Kaplan, David, Chiocca, E. Antonio, Uchida, Hiroaki, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., van Kuppevelt, Toin H., Mo, Xiaokui, Cripe, Timothy P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609913/
https://www.ncbi.nlm.nih.gov/pubmed/23254370
http://dx.doi.org/10.1038/gt.2012.93