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The CSB repair factor is overexpressed in cancer cells, increases apoptotic resistance, and promotes tumor growth

In the present study we show that a number of cancer cell lines from different tissues display dramatically increased expression of the Cockayne Syndrome group B (CSB) protein, a DNA repair factor, that has recently been shown to be involved in cell robustness. Furthermore, we demonstrated that abla...

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Detalles Bibliográficos
Autores principales: Caputo, Manuela, Frontini, Mattia, Velez-Cruz, Renier, Nicolai, Serena, Prantera, Giorgio, Proietti-De-Santis, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610032/
https://www.ncbi.nlm.nih.gov/pubmed/23419237
http://dx.doi.org/10.1016/j.dnarep.2013.01.008