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Extreme Depletion of PIP(3) Accompanies the Increased Life Span and Stress Tolerance of PI3K-null C. elegans Mutants
The regulation of animal longevity shows remarkable plasticity, in that a variety of genetic lesions are able to extend lifespan by as much as 10-fold. Such studies have implicated several key signaling pathways that must normally limit longevity, since their disruption prolongs life. Little is know...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610087/ https://www.ncbi.nlm.nih.gov/pubmed/23543623 http://dx.doi.org/10.3389/fgene.2013.00034 |