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Effects of ectopic HER-2/neu gene expression on the COX-2/PGE(2)/P450arom signaling pathway in endometrial carcinoma cells: HER-2/neu gene expression in endometrial carcinoma cells

OBJECTIVES: To investigate the role of HER-2/neu-mediated COX-2/P450arom signal in estrogen-dependent endometrial carcinoma. METHODS: The recombinant eukaryotic expression vector, pcDNA3.1-HER-2/neu, was constructed and transfect to Ishikawa endometrial carcinoma cells. The expression of COX-2 and P...

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Detalles Bibliográficos
Autores principales: Li, Shu, Ma, XiaoXin, Ma, Li, Wang, Cuicui, He, YuanQi, Yu, ZhiJuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610111/
https://www.ncbi.nlm.nih.gov/pubmed/23453006
http://dx.doi.org/10.1186/1756-9966-32-11