Aβ impairs nicotinic regulation of inhibitory synaptic transmission and interneuron excitability in prefrontal cortex

BACKGROUND: Accumulation of β-amyloid (Aβ) and cholinergic deficiency are two prominent features of Alzheimer’s disease (AD). To understand how Aβ-induced dysfunction of the nicotinic system may contribute to cognitive impairment in AD, we examined the effect of Aβ on nicotinic regulation of synapti...

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Detalles Bibliográficos
Autores principales: Chen, Guo-Jun, Xiong, Zhe, Yan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610117/
https://www.ncbi.nlm.nih.gov/pubmed/23327202
http://dx.doi.org/10.1186/1750-1326-8-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610117/
https://www.ncbi.nlm.nih.gov/pubmed/23327202
http://dx.doi.org/10.1186/1750-1326-8-3

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