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BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy

BACKGROUND: B-cell dysregulation has been implicated but not fully characterized in pediatric opsoclonus-myoclonus syndrome (OMS), a neuroblastoma-associated neuroinflammatory disorder. OBJECTIVE: To assess the role of B-cell activating factor (BAFF) and a proliferation-inducing ligand (APRIL), two...

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Detalles Bibliográficos
Autores principales: Pranzatelli, Michael R, Tate, Elizabeth D, McGee, Nathan R, Travelstead, Anna L, Colliver, Jerry A, Ness, Jayne M, Ransohoff, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610127/
https://www.ncbi.nlm.nih.gov/pubmed/23324534
http://dx.doi.org/10.1186/1742-2094-10-10