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Structure-based drug design studies of UDP-N-acetylglucosamine pyrophosphosrylase, a key enzyme for the control of witches’ broom disease

BACKGROUND: The witches’ broom disease is a plague caused by Moniliophthora perniciosa in the Theobroma cacao, which has been reducing the cocoa production since 1989. This issue motivated a genome project that has showing several new molecular targets, which can be developed inhibitors in order to...

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Detalles Bibliográficos
Autores principales: Junior, Manoelito C Santos, de Assis, Sandra Aparecida, Góes-Neto, Aristóteles, Duarte, Ângelo Amâncio, Alves, Ricardo José, Junior, Moacyr Comar, Taranto, Alex Gutterres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610160/
https://www.ncbi.nlm.nih.gov/pubmed/23497581
http://dx.doi.org/10.1186/1752-153X-7-48