Correction of unexpected distributions of P values from analysis of whole genome arrays by rectifying violation of statistical assumptions

BACKGROUND: Statistical analysis of genome-wide microarrays can result in many thousands of identical statistical tests being performed as each probe is tested for an association with a phenotype of interest. If there were no association between any of the probes and the phenotype, the distribution...

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Detalles Bibliográficos
Autores principales: Barton, Sheila J, Crozier, Sarah R, Lillycrop, Karen A, Godfrey, Keith M, Inskip, Hazel M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610227/
https://www.ncbi.nlm.nih.gov/pubmed/23496791
http://dx.doi.org/10.1186/1471-2164-14-161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610227/
https://www.ncbi.nlm.nih.gov/pubmed/23496791
http://dx.doi.org/10.1186/1471-2164-14-161

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