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Correction of unexpected distributions of P values from analysis of whole genome arrays by rectifying violation of statistical assumptions
BACKGROUND: Statistical analysis of genome-wide microarrays can result in many thousands of identical statistical tests being performed as each probe is tested for an association with a phenotype of interest. If there were no association between any of the probes and the phenotype, the distribution...
Autores principales: | Barton, Sheila J, Crozier, Sarah R, Lillycrop, Karen A, Godfrey, Keith M, Inskip, Hazel M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610227/ https://www.ncbi.nlm.nih.gov/pubmed/23496791 http://dx.doi.org/10.1186/1471-2164-14-161 |
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