The impact of KRAS mutations on VEGF-A production and tumour vascular network

BACKGROUND: The malignant potential of tumour cells may be influenced by the molecular nature of KRAS mutations being codon 13 mutations less aggressive than codon 12 ones. Their metabolic profile is also different, with an increased anaerobic glycolytic metabolism in cells harbouring codon 12 KRAS...

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Detalles Bibliográficos
Autores principales: Figueras, Agnès, Arbos, Maria Antonia, Quiles, Maria Teresa, Viñals, Francesc, Germà, Josep Ramón, Capellà, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610256/
https://www.ncbi.nlm.nih.gov/pubmed/23506169
http://dx.doi.org/10.1186/1471-2407-13-125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610256/
https://www.ncbi.nlm.nih.gov/pubmed/23506169
http://dx.doi.org/10.1186/1471-2407-13-125

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