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Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice

BACKGROUND: Pim (proviral insertion in murine lymphoma) kinases are a small family of constitutively active, highly conservative serine/threonine oncogenic kinases and have 3 members: Pim1, Pim2, and Pim3. Pim kinases are also implicated in the regulation of B- and T- cell responses to cytokines and...

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Detalles Bibliográficos
Autores principales: An, Ningfei, Kraft, Andrew S, Kang, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610283/
https://www.ncbi.nlm.nih.gov/pubmed/23360755
http://dx.doi.org/10.1186/1756-8722-6-12