Cargando…

Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice

BACKGROUND: Pim (proviral insertion in murine lymphoma) kinases are a small family of constitutively active, highly conservative serine/threonine oncogenic kinases and have 3 members: Pim1, Pim2, and Pim3. Pim kinases are also implicated in the regulation of B- and T- cell responses to cytokines and...

Descripción completa

Detalles Bibliográficos
Autores principales:	An, Ningfei, Kraft, Andrew S, Kang, Yubin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610283/ https://www.ncbi.nlm.nih.gov/pubmed/23360755 http://dx.doi.org/10.1186/1756-8722-6-12

Ejemplares similares

Pim1 kinase regulates c-Kit gene translation
por: An, Ningfei, et al.
Publicado: (2016)

PIM Kinases in Multiple Myeloma
por: Wu, Jian, et al.
Publicado: (2021)

Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset
por: Padi, Sathish K.R., et al.
Publicado: (2017)

Deletion of Pim Kinases Elevates the Cellular Levels of Reactive Oxygen Species and Sensitizes to K-Ras-Induced Cell Killing
por: Song, Jin H., et al.
Publicado: (2014)

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice
por: Wilson, Robert, et al.
Publicado: (2017)

PIM-1 kinase: a potential biomarker of triple-negative breast cancer
por: Chen, Jieying, et al.
Publicado: (2019)

Diacylglycerol Kinase β Knockout Mice Exhibit Lithium-Sensitive Behavioral Abnormalities
por: Kakefuda, Kenichi, et al.
Publicado: (2010)

Insulin receptor substrate 1 is a substrate of the Pim protein kinases
por: Song, Jin H., et al.
Publicado: (2016)

The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets
por: Saurabh, Kumar, et al.
Publicado: (2014)

A review on PIM kinases in tumors
por: Arrouchi, Housna, et al.
Publicado: (2019)

Triple selectin knockout (ELP-/-) mice fail to develop OVA-induced acute asthma phenotype
por: Banerjee, Ena Ray
Publicado: (2011)

The role of PIM1/PIM2 kinases in tumors of the male reproductive system
por: Jiménez-García, Manuel Pedro, et al.
Publicado: (2016)

Behavioral and Neuroanatomical Abnormalities in Pleiotrophin Knockout Mice
por: Krellman, Jason W., et al.
Publicado: (2014)

Targeting the Pim kinases in multiple myeloma
por: Keane, N A, et al.
Publicado: (2015)

PIM Kinase as an Executional Target in Cancer
por: Zhang, Xinning, et al.
Publicado: (2018)

Protein kinase PIM2: A simple PIM family kinase with complex functions in cancer metabolism and therapeutics
por: Wang, Yixin, et al.
Publicado: (2021)

Inflammation and stem markers association to PIM1/PIM2 kinase-induced tumors in breast and uterus
por: Jiménez-García, Manuel-Pedro, et al.
Publicado: (2017)

Behavioral Abnormalities in Knockout and Humanized Tau Mice
por: Gonçalves, Rafaella Araujo, et al.
Publicado: (2020)

Autism-related behavioral abnormalities in synapsin knockout mice
por: Greco, Barbara, et al.
Publicado: (2013)

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion
por: Santio, Niina M, et al.
Publicado: (2010)

The Role of PIM Kinases in Pediatric Solid Tumors
por: Julson, Janet Rae, et al.
Publicado: (2022)

Targeting PIM Kinases to Improve the Efficacy of Immunotherapy
por: Clements, Amber N., et al.
Publicado: (2022)

[Retracted] Expression and function of PIM kinases in osteosarcoma
por: Mou, Shuai, et al.
Publicado: (2023)

Pim Kinases: Important Regulators of Cardiovascular Disease
por: Nock, Sophie, et al.
Publicado: (2023)

Pim1 knockout alleviates sarcopenia in aging mice via reducing adipogenic differentiation of PDGFRα(+) mesenchymal progenitors
por: Shang, Guo‐kai, et al.
Publicado: (2021)

PIM kinases as therapeutic targets against advanced melanoma
por: Shannan, Batool, et al.
Publicado: (2016)

Diacylglycerol Kinase β Knockout Mice Exhibit Attention-Deficit Behavior and an Abnormal Response on Methylphenidate-Induced Hyperactivity
por: Ishisaka, Mitsue, et al.
Publicado: (2012)

Comprehensive behavioral phenotyping of calpastatin-knockout mice
por: Nakajima, Ryuichi, et al.
Publicado: (2008)

Anti‐tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL‐302 in neuroblastoma
por: Mohlin, Sofie, et al.
Publicado: (2019)

Anti‐tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL‐302 in neuroblastoma
por: Mohlin, Sofie, et al.
Publicado: (2020)

Abnormal fluid homeostasis in apelin receptor knockout mice
por: Roberts, Emma M, et al.
Publicado: (2009)

Erratum: Behavioral Abnormalities in Knockout and Humanized Tau Mice
Publicado: (2021)

Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas
por: Kreuz, S., et al.
Publicado: (2015)

PIM kinases mediate resistance to cisplatin chemotherapy in hepatoblastoma
por: Marayati, Raoud, et al.
Publicado: (2021)

Expression and ERG regulation of PIM kinases in prostate cancer
por: Eerola, Sini K., et al.
Publicado: (2021)

An overview of pim kinase as a target in multiple myeloma
por: Liu, Zhaoyun, et al.
Publicado: (2023)

Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor
por: Bullock, Alex N., et al.
Publicado: (2009)

Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma
por: Stafman, Laura L., et al.
Publicado: (2018)

Targeting PIM kinases to oppose hypoxia-mediated therapeutic resistance
por: Chauhan, Shailender S., et al.
Publicado: (2018)

P044: PIM kinases support protumoral and immunosuppressive phenotype and functions of macrophages in classical Hodgkin Lymphoma
por: Szydłowski, Maciej, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5i89p9game43fs1rm9cn6j1225