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Differential Cytotoxicity Responses by Dog and Rat Hepatocytes to Phospholipogenic Treatments
Dog and rat hepatocytes were treated with phospholipogenics to identify the more sensitive species and to determine whether lysosomal or mitochondrial changes were the primary cause of cytotoxicity. Endpoints included cell death, lysosome membrane integrity, mitochondrial membrane polarization, and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610344/ https://www.ncbi.nlm.nih.gov/pubmed/23577025 http://dx.doi.org/10.1155/2013/956404 |