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Differential Cytotoxicity Responses by Dog and Rat Hepatocytes to Phospholipogenic Treatments

Dog and rat hepatocytes were treated with phospholipogenics to identify the more sensitive species and to determine whether lysosomal or mitochondrial changes were the primary cause of cytotoxicity. Endpoints included cell death, lysosome membrane integrity, mitochondrial membrane polarization, and...

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Detalles Bibliográficos
Autores principales: Morelli, James K., Ciaccio, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610344/
https://www.ncbi.nlm.nih.gov/pubmed/23577025
http://dx.doi.org/10.1155/2013/956404