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Triptolide Prevents Bone Destruction in the Collagen-Induced Arthritis Model of Rheumatoid Arthritis by Targeting RANKL/RANK/OPG Signal Pathway

Focal bone destruction within inflamed joints is the most specific hallmark of rheumatoid arthritis (RA). Our previous study indicated that the therapeutic efficiency of triptolide in RA may be due partially to its chondroprotective and anti-inflammatory effects. However, its roles in bone destructi...

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Detalles Bibliográficos
Autores principales: Liu, Chunfang, Zhang, Yanqiong, Kong, Xiangying, Zhu, Liuluan, Pang, Jian, Xu, Ying, Chen, Weiheng, Zhan, Hongsheng, Lu, Aiping, Lin, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610373/
https://www.ncbi.nlm.nih.gov/pubmed/23573139
http://dx.doi.org/10.1155/2013/626038