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Subtype-selective regulation of IP(3) receptors by thimerosal via cysteine residues within the IP(3)-binding core and suppressor domain
IP(3)R (IP(3) [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca(2+) channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP(3)R, low concentrations of thimerosal (also known as t...
Autores principales: | Khan, Samir A., Rossi, Ana M., Riley, Andrew M., Potter, Barry V. L., Taylor, Colin W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610541/ https://www.ncbi.nlm.nih.gov/pubmed/23282150 http://dx.doi.org/10.1042/BJ20121600 |
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