Elevated Expression of the Integrin-Associated Protein PINCH Suppresses the Defects of Drosophila melanogaster Muscle Hypercontraction Mutants

A variety of human diseases arise from mutations that alter muscle contraction. Evolutionary conservation allows genetic studies in Drosophila melanogaster to be used to better understand these myopathies and suggest novel therapeutic strategies. Integrin-mediated adhesion is required to support mus...

Descripción completa

Detalles Bibliográficos
Autores principales: Pronovost, Stephen M., Beckerle, Mary C., Kadrmas, Julie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610608/
https://www.ncbi.nlm.nih.gov/pubmed/23555310
http://dx.doi.org/10.1371/journal.pgen.1003406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610608/
https://www.ncbi.nlm.nih.gov/pubmed/23555310
http://dx.doi.org/10.1371/journal.pgen.1003406

Ejemplares similares