CRL2(LRR-1) E3-Ligase Regulates Proliferation and Progression through Meiosis in the Caenorhabditis elegans Germline

The ubiquitin-proteolytic system controls the stability of proteins in space and time. In this study, using a temperature-sensitive mutant allele of the cul-2 gene, we show that CRL2(LRR-1) (CUL-2 RING E3 ubiquitin-ligase and the Leucine Rich Repeat 1 substrate recognition subunit) acts at multiple...

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Detalles Bibliográficos
Autores principales: Burger, Julien, Merlet, Jorge, Tavernier, Nicolas, Richaudeau, Bénédicte, Arnold, Andreas, Ciosk, Rafal, Bowerman, Bruce, Pintard, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610609/
https://www.ncbi.nlm.nih.gov/pubmed/23555289
http://dx.doi.org/10.1371/journal.pgen.1003375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610609/
https://www.ncbi.nlm.nih.gov/pubmed/23555289
http://dx.doi.org/10.1371/journal.pgen.1003375

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