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Explaining the Determinants of First Phase HIV Decay Dynamics through the Effects of Stage-dependent Drug Action

A recent investigation of the effect of different antiretroviral drug classes on first phase dynamics of HIV RNA plasma virus levels has indicated that drugs acting at stages closer to viral production, such as the integrase inhibitor raltegravir, can produce a steeper first phase decay slope that m...

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Detalles Bibliográficos
Autores principales: Gilmore, James B., Kelleher, Anthony D., Cooper, David A., Murray, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610612/
https://www.ncbi.nlm.nih.gov/pubmed/23555209
http://dx.doi.org/10.1371/journal.pcbi.1002971