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Long Interspersed Element–1 (LINE-1): Passenger or Driver in Human Neoplasms?
LINE-1 (L1) retrotransposons make up a significant portion of human genomes, with an estimated 500,000 copies per genome. Like other retrotransposons, L1 retrotransposons propagate through RNA sequences that are reverse transcribed into DNA sequences, which are integrated into new genomic loci. L1 s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610623/ https://www.ncbi.nlm.nih.gov/pubmed/23555307 http://dx.doi.org/10.1371/journal.pgen.1003402 |