HSV-2 Specifically Down Regulates HLA-C Expression to Render HSV-2-Infected DCs Susceptible to NK Cell Killing

Both NK cells and CTLs kill virus-infected and tumor cells. However, the ways by which these killer cells recognize the infected or the tumorigenic cells are different, in fact almost opposite. CTLs are activated through the interaction of the TCR with MHC class I proteins. In contrast, NK cells are...

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Detalles Bibliográficos
Autores principales: Elboim, Moran, Grodzovski, Inna, Djian, Esther, Wolf, Dana G., Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610627/
https://www.ncbi.nlm.nih.gov/pubmed/23555244
http://dx.doi.org/10.1371/journal.ppat.1003226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610627/
https://www.ncbi.nlm.nih.gov/pubmed/23555244
http://dx.doi.org/10.1371/journal.ppat.1003226

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