Cargando…

Colocalization of Coregulated Genes: A Steered Molecular Dynamics Study of Human Chromosome 19

The connection between chromatin nuclear organization and gene activity is vividly illustrated by the observation that transcriptional coregulation of certain genes appears to be directly influenced by their spatial proximity. This fact poses the more general question of whether it is at all feasibl...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Stefano, Marco, Rosa, Angelo, Belcastro, Vincenzo, di Bernardo, Diego, Micheletti, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610629/
https://www.ncbi.nlm.nih.gov/pubmed/23555238
http://dx.doi.org/10.1371/journal.pcbi.1003019