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Colocalization of Coregulated Genes: A Steered Molecular Dynamics Study of Human Chromosome 19
The connection between chromatin nuclear organization and gene activity is vividly illustrated by the observation that transcriptional coregulation of certain genes appears to be directly influenced by their spatial proximity. This fact poses the more general question of whether it is at all feasibl...
Autores principales: | Di Stefano, Marco, Rosa, Angelo, Belcastro, Vincenzo, di Bernardo, Diego, Micheletti, Cristian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610629/ https://www.ncbi.nlm.nih.gov/pubmed/23555238 http://dx.doi.org/10.1371/journal.pcbi.1003019 |
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