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Spreading of a Prion Domain from Cell-to-Cell by Vesicular Transport in Caenorhabditis elegans
Prion proteins can adopt self-propagating alternative conformations that account for the infectious nature of transmissible spongiform encephalopathies (TSEs) and the epigenetic inheritance of certain traits in yeast. Recent evidence suggests a similar propagation of misfolded proteins in the spread...
Autores principales: | Nussbaum-Krammer, Carmen I., Park, Kyung-Won, Li, Liming, Melki, Ronald, Morimoto, Richard I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610634/ https://www.ncbi.nlm.nih.gov/pubmed/23555277 http://dx.doi.org/10.1371/journal.pgen.1003351 |
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