The Role of ATM in the Deficiency in Nonhomologous End-Joining near Telomeres in a Human Cancer Cell Line

Telomeres distinguish chromosome ends from double-strand breaks (DSBs) and prevent chromosome fusion. However, telomeres can also interfere with DNA repair, as shown by a deficiency in nonhomologous end joining (NHEJ) and an increase in large deletions at telomeric DSBs. The sensitivity of telomeric...

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Detalles Bibliográficos
Autores principales: Muraki, Keiko, Han, Limei, Miller, Douglas, Murnane, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610639/
https://www.ncbi.nlm.nih.gov/pubmed/23555296
http://dx.doi.org/10.1371/journal.pgen.1003386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610639/
https://www.ncbi.nlm.nih.gov/pubmed/23555296
http://dx.doi.org/10.1371/journal.pgen.1003386

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