Endogenous IL-21 regulates pathogenic mucosal CD4 T-cell responses during enhanced RSV disease in mice

A role for interleukin-21 (IL-21) has recently been found in several diseases, but contribution to mucosal defences has not been described. In BALB/c mice infected with respiratory syncytial virus (RSV), IL-21 depletion had little effect in primary infection. However, depletion of mice during primin...

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Detalles Bibliográficos
Autores principales: Dodd, J S, Clark, D, Muir, R, Korpis, C, Openshaw, P J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610641/
https://www.ncbi.nlm.nih.gov/pubmed/23168836
http://dx.doi.org/10.1038/mi.2012.108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610641/
https://www.ncbi.nlm.nih.gov/pubmed/23168836
http://dx.doi.org/10.1038/mi.2012.108

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