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Endogenous IL-21 regulates pathogenic mucosal CD4 T-cell responses during enhanced RSV disease in mice
A role for interleukin-21 (IL-21) has recently been found in several diseases, but contribution to mucosal defences has not been described. In BALB/c mice infected with respiratory syncytial virus (RSV), IL-21 depletion had little effect in primary infection. However, depletion of mice during primin...
Autores principales: | Dodd, J S, Clark, D, Muir, R, Korpis, C, Openshaw, P J M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610641/ https://www.ncbi.nlm.nih.gov/pubmed/23168836 http://dx.doi.org/10.1038/mi.2012.108 |
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