Cargando…

Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing

To develop new approaches to control HIV-1 replication, we examined the capacity of recently described small molecular modulators of RNA splicing for their effects on viral RNA metabolism. Of the drugs tested, digoxin was found to induce a dramatic inhibition of HIV-1 structural protein synthesis, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Raymond W., Balachandran, Ahalya, Ostrowski, Mario A., Cochrane, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610647/
https://www.ncbi.nlm.nih.gov/pubmed/23555254
http://dx.doi.org/10.1371/journal.ppat.1003241