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Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing
To develop new approaches to control HIV-1 replication, we examined the capacity of recently described small molecular modulators of RNA splicing for their effects on viral RNA metabolism. Of the drugs tested, digoxin was found to induce a dramatic inhibition of HIV-1 structural protein synthesis, a...
Autores principales: | Wong, Raymond W., Balachandran, Ahalya, Ostrowski, Mario A., Cochrane, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610647/ https://www.ncbi.nlm.nih.gov/pubmed/23555254 http://dx.doi.org/10.1371/journal.ppat.1003241 |
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