CYP2D6 Genotype Dependent Oxycodone Metabolism in Postoperative Patients

BACKGROUND: The impact of polymorphic cytochrome P450 CYP2D6 enzyme on oxycodone's metabolism and clinical efficacy is currently being discussed. However, there are only spare data from postoperative settings. The hypothesis of this study is that genotype dependent CYP2D6 activity influences pl...

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Detalles Bibliográficos
Autores principales: Stamer, Ulrike M., Zhang, Lan, Book, Malte, Lehmann, Lutz E., Stuber, Frank, Musshoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610662/
https://www.ncbi.nlm.nih.gov/pubmed/23555934
http://dx.doi.org/10.1371/journal.pone.0060239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610662/
https://www.ncbi.nlm.nih.gov/pubmed/23555934
http://dx.doi.org/10.1371/journal.pone.0060239

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