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CYP2D6 Genotype Dependent Oxycodone Metabolism in Postoperative Patients
BACKGROUND: The impact of polymorphic cytochrome P450 CYP2D6 enzyme on oxycodone's metabolism and clinical efficacy is currently being discussed. However, there are only spare data from postoperative settings. The hypothesis of this study is that genotype dependent CYP2D6 activity influences pl...
Autores principales: | Stamer, Ulrike M., Zhang, Lan, Book, Malte, Lehmann, Lutz E., Stuber, Frank, Musshoff, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610662/ https://www.ncbi.nlm.nih.gov/pubmed/23555934 http://dx.doi.org/10.1371/journal.pone.0060239 |
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