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Breakdown of Methods for Phasing and Imputation in the Presence of Double Genotype Sharing
In genome-wide association studies, results have been improved through imputation of a denser marker set based on reference haplotypes and phasing of the genotype data. To better handle very large sets of reference haplotypes, pre-phasing with only study individuals has been suggested. We present a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610665/ https://www.ncbi.nlm.nih.gov/pubmed/23555958 http://dx.doi.org/10.1371/journal.pone.0060354 |