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Breakdown of Methods for Phasing and Imputation in the Presence of Double Genotype Sharing

In genome-wide association studies, results have been improved through imputation of a denser marker set based on reference haplotypes and phasing of the genotype data. To better handle very large sets of reference haplotypes, pre-phasing with only study individuals has been suggested. We present a...

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Detalles Bibliográficos
Autor principal: Nettelblad, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610665/
https://www.ncbi.nlm.nih.gov/pubmed/23555958
http://dx.doi.org/10.1371/journal.pone.0060354

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