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Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy
Hepatitis C Virus (HCV) induces intracellular events that trigger mitochondrial dysfunction and promote host metabolic alterations. Here, we investigated selective autophagic degradation of mitochondria (mitophagy) in HCV-infected cells. HCV infection stimulated Parkin and PINK1 gene expression, ind...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610669/ https://www.ncbi.nlm.nih.gov/pubmed/23555273 http://dx.doi.org/10.1371/journal.ppat.1003285 |