Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy

Hepatitis C Virus (HCV) induces intracellular events that trigger mitochondrial dysfunction and promote host metabolic alterations. Here, we investigated selective autophagic degradation of mitochondria (mitophagy) in HCV-infected cells. HCV infection stimulated Parkin and PINK1 gene expression, ind...

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Detalles Bibliográficos
Autores principales: Kim, Seong-Jun, Syed, Gulam H., Siddiqui, Aleem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610669/
https://www.ncbi.nlm.nih.gov/pubmed/23555273
http://dx.doi.org/10.1371/journal.ppat.1003285

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