Prevention of LPS-Induced Microglia Activation, Cytokine Production and Sickness Behavior with TLR4 Receptor Interfering Peptides

The innate immune receptor Toll-like 4 (TLR4) is the receptor activated by lipopolysaccharide (LPS), and TLR4-LPS interaction is well known to induce an innate immune response, triggering sickness behavior. Within the brain, TLR4 is highly expressed in brain microglia, and excessive inflammation res...

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Detalles Bibliográficos
Autores principales: Hines, Dustin J., Choi, Hyun B., Hines, Rochelle M., Phillips, Anthony G., MacVicar, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610686/
https://www.ncbi.nlm.nih.gov/pubmed/23555964
http://dx.doi.org/10.1371/journal.pone.0060388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610686/
https://www.ncbi.nlm.nih.gov/pubmed/23555964
http://dx.doi.org/10.1371/journal.pone.0060388

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