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Impaired Endothelial Progenitor Cell Mobilization and Dysfunctional Bone Marrow Stroma in Diabetes Mellitus

BACKGROUND: Circulating Endothelial Progenitor Cell (EPC) levels are reduced in diabetes mellitus. This may be a consequence of impaired mobilization of EPC from the bone marrow. We hypothesized that under diabetic conditions, mobilization of EPC from the bone marrow to the circulation is impaired –...

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Detalles Bibliográficos
Autores principales: Westerweel, Peter E., Teraa, Martin, Rafii, Shahin, Jaspers, Janneke E., White, Ian A., Hooper, Andrea T., Doevendans, Pieter A., Verhaar, Marianne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610687/
https://www.ncbi.nlm.nih.gov/pubmed/23555959
http://dx.doi.org/10.1371/journal.pone.0060357