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Differential Regulation of Matrix-Metalloproteinases and Their Tissue Inhibitors in Patients with Aneurysmal Subarachnoid Hemorrhage

BACKGROUND: Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in vascular remodeling, (neuro)inflammation, blood-brain barrier breakdown and neuronal apoptosis. Proinflammatory mechanisms are suggested to play an important role during early brain injury and cerebral v...

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Detalles Bibliográficos
Autores principales: Fischer, Marlene, Dietmann, Anelia, Beer, Ronny, Broessner, Gregor, Helbok, Raimund, Pfausler, Bettina, Schmutzhard, Erich, Lackner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610709/
https://www.ncbi.nlm.nih.gov/pubmed/23555845
http://dx.doi.org/10.1371/journal.pone.0059952