Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage

How Fanconi anemia (FA) protein D2 (FANCD2) performs DNA damage repair remains largely elusive. We report here that translesion synthesis DNA polymerase (pol) eta is a novel mediator of FANCD2 function. We found that wild type (wt) FANCD2, not K561R (mt) FANCD2, can interact with pol eta. Upon DNA d...

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Detalles Bibliográficos
Autores principales: Fu, Dechen, Dudimah, Fred Duafalia, Zhang, Jun, Pickering, Anna, Paneerselvam, Jayabal, Palrasu, Manikandan, Wang, Hong, Fei, Peiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610727/
https://www.ncbi.nlm.nih.gov/pubmed/23388460
http://dx.doi.org/10.4161/cc.23755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610727/
https://www.ncbi.nlm.nih.gov/pubmed/23388460
http://dx.doi.org/10.4161/cc.23755

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