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Expression of the Glioma-Associated Oncogene Homolog 1 (Gli1) in Advanced Serous Ovarian Cancer Is Associated with Unfavorable Overall Survival

Recent evidence links aberrant activation of Hedgehog (Hh) signaling with the pathogenesis of several cancers including medulloblastoma, glioblastoma, melanoma as well as pancreas, colorectal, and prostate carcinomas. Here we investigated the role of the transcription factor Gli1 in ovarian cancer....

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Detalles Bibliográficos
Autores principales: Ciucci, Alessandra, De Stefano, Ilaria, Vellone, Valerio Gaetano, Lisi, Lucia, Bottoni, Carolina, Scambia, Giovanni, Zannoni, Gian Franco, Gallo, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610749/
https://www.ncbi.nlm.nih.gov/pubmed/23555905
http://dx.doi.org/10.1371/journal.pone.0060145