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Robust Prediction of Expression Differences among Human Individuals Using Only Genotype Information

Many genetic variants that are significantly correlated to gene expression changes across human individuals have been identified, but the ability of these variants to predict expression of unseen individuals has rarely been evaluated. Here, we devise an algorithm that, given training expression and...

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Detalles Bibliográficos
Autores principales: Manor, Ohad, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610805/
https://www.ncbi.nlm.nih.gov/pubmed/23555302
http://dx.doi.org/10.1371/journal.pgen.1003396