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C. elegans Ring Finger Protein RNF-113 Is Involved in Interstrand DNA Crosslink Repair and Interacts with a RAD51C Homolog

The Fanconi anemia (FA) pathway recognizes interstrand DNA crosslinks (ICLs) and contributes to their conversion into double-strand DNA breaks, which can be repaired by homologous recombination. Seven orthologs of the 15 proteins associated with Fanconi anemia are functionally conserved in the model...

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Detalles Bibliográficos
Autores principales: Lee, Hyojin, Alpi, Arno F., Park, Mi So, Rose, Ann, Koo, Hyeon-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610817/
https://www.ncbi.nlm.nih.gov/pubmed/23555887
http://dx.doi.org/10.1371/journal.pone.0060071