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The Smc5/Smc6/MAGE Complex Confers Resistance to Caffeine and Genotoxic Stress in Drosophila melanogaster

The SMC5/6 protein complex consists of the Smc5, Smc6 and Non-Smc-Element (Nse) proteins and is important for genome stability in many species. To identify novel components in the DNA repair pathway, we carried out a genetic screen to identify mutations that confer reduced resistance to the genotoxi...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Zhuo, Ran, Tiong, Stanley, Di Cara, Francesca, King-Jones, Kirst, Hughes, Sarah C., Campbell, Shelagh D., Wevrick, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610895/
https://www.ncbi.nlm.nih.gov/pubmed/23555814
http://dx.doi.org/10.1371/journal.pone.0059866