Silencing of RASSF3 by DNA Hypermethylation Is Associated with Tumorigenesis in Somatotroph Adenomas

The pathogenic mechanisms underlying pituitary somatotroph adenoma formation, progression are poorly understood. To identify candidate tumor suppressor genes involved in pituitary somatotroph adenoma tumorigenesis, we used HG18 CpG plus Promoter Microarray in 27 human somatotroph adenomas and 4 norm...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Hu, Liu, Huanhai, Zhao, Shuwei, Wu, Jian, Fan, Jingping, Liao, Jianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610897/
https://www.ncbi.nlm.nih.gov/pubmed/23555615
http://dx.doi.org/10.1371/journal.pone.0059024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610897/
https://www.ncbi.nlm.nih.gov/pubmed/23555615
http://dx.doi.org/10.1371/journal.pone.0059024

Ejemplares similares