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Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping

Located on Chromosome 6p21, classical human leukocyte antigen genes are highly polymorphic. HLA alleles associate with a variety of phenotypes, such as narcolepsy, autoimmunity, as well as immunologic response to infectious disease. Moreover, high resolution genotyping of these loci is critical to a...

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Detalles Bibliográficos
Autores principales: Ringquist, Steven, Bellone, Gaia, Lu, Ying, Roeder, Kathryn, Trucco, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610899/
https://www.ncbi.nlm.nih.gov/pubmed/23555798
http://dx.doi.org/10.1371/journal.pone.0059835