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Clustering and Alignment of Polymorphic Sequences for HLA-DRB1 Genotyping
Located on Chromosome 6p21, classical human leukocyte antigen genes are highly polymorphic. HLA alleles associate with a variety of phenotypes, such as narcolepsy, autoimmunity, as well as immunologic response to infectious disease. Moreover, high resolution genotyping of these loci is critical to a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610899/ https://www.ncbi.nlm.nih.gov/pubmed/23555798 http://dx.doi.org/10.1371/journal.pone.0059835 |